A homogenized cerebrospinal fluid model for diffuse optical tomography in the neonatal head - Groupe de Recherche sur l'Analyse Multimodale de la Fonction Cérébrale - UMR INSERM_S 1105 Accéder directement au contenu
Article Dans Une Revue International Journal for Numerical Methods in Biomedical Engineering Année : 2021

A homogenized cerebrospinal fluid model for diffuse optical tomography in the neonatal head

Résumé

Diffuse optical tomography is a non-invasive and non-irradiating medical imaging technique that is particularly suitable for cerebral monitoring of newborns since it can be used at the bedside of the patient. Here, a new model for optical tomography in the neonatal brain is presented that takes into account the presence of arachnoid trabeculæ in the cerebrospinal fluid (CSF). It is known that the classical diffusion approximation (DA) for light propagation is at the limit of validity in the CSF layer due to the low values of the absorption and scattering coefficients. The new model is obtained by the DA of the homogenized radiative transfer equation and is rigorously justified. Numerical results in two and three dimensions attest for the improved sensitivity of the new model to the presence of perturbations in the brain layer.
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Dates et versions

hal-03144383 , version 1 (17-02-2021)

Identifiants

Citer

Stephanie Lohrengel, Farah Oumri, Stéphanie Salmon, Fabrice Wallois, Mahdi Mahmoudzadeh. A homogenized cerebrospinal fluid model for diffuse optical tomography in the neonatal head. International Journal for Numerical Methods in Biomedical Engineering, 2021, ⟨10.1002/cnm.3538⟩. ⟨hal-03144383⟩
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