Human resting-state EEG and radiofrequency GSM mobile phone exposure: the impact of the individual alpha frequency

Jasmina Wallace (1, 2, 3) , Lydia Yahia-Cherif (4) , Christophe Gitton (4) , Laurent Hugueville (4) , Jean-Didier Lemaréchal (4) , Brahim Selmaoui (1, 2)

1 INERIS - Institut National de l'Environnement Industriel et des Risques
2 PERITOX - Périnatalité et Risques Toxiques - UMR INERIS_I 1
3 IRBA - Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge]
4 CENIR - Plateforme de neuroimagerie CENIR = Center for NeuroImaging Research-Human MRI Neuroimaging core facility for clinical research [ICM Paris]

Purpose : With the extensive use of mobile phone (MP), several studies have been realized to investigate the effects of radiofrequency electromagnetic fields (RF-EMF) exposure on brain activity at rest via electroencephalography (EEG), and the most consistent effect has been seen on the alpha band power spectral density (PSD). However, some studies reported an increase or a decrease of the PSD, while others showed no effect. It has been suggested that these differences might partly be due to a variability of the physiological state of the brain between subjects. So, the aim of this study was to investigate the alpha band modulation, exploring the impact of the alpha band frequency ranges applied in the PSD analysis. Materials and Methods : Twenty-one healthy volunteers took part to the study with a double-blind, randomized and counterbalanced crossover design, during which eyes-open (EO) and eyes-closed (EC) resting-state EEG was recorded. The exposure system was a sham or a real GSM (global system for mobile) 900 MHz MP (pulse modulated at 217 Hz, mean power of 250 mW and 2 W peak, with a maximum specific absorption rate of 0.70 W/kg on 1 g tissue). The experimental protocol presented a baseline recording phase without MP exposure, an exposure phase during which the exposure system was placed against the left ear, and the post-exposure phase without MP. EEG data from baseline and exposure phases were analyzed and PSD was computed for the alpha band in the fixed range of 8–12 Hz and for the individual alpha band frequency range (IAF). Results : Results showed a trend in decrease or increase of EEG power of both alpha oscillations during exposure in relation to EC and EO recording conditions, respectively, but not reaching statistical significance. Findings did not provide evidence for a different sensitivity to RF-EMF MP related to individual variability in the frequency of the alpha band. Conclusion : In conclusion, these results did not show alpha band activity modulation during resting-state under RF-EMF. It might be argued the need of a delay after the exposure in order to appreciate an EEG spectral power modulation related to RF-EMF exposure.

Mots clés: Non-ionizing radiation; radiofrequency; EEG; resting-state; individual alpha band

Domaines: Neurosciences; Toxicologie

Jasmina Wallace, Lydia Yahia-Cherif, Christophe Gitton, Laurent Hugueville, Jean-Didier Lemaréchal, et al.. Human resting-state EEG and radiofrequency GSM mobile phone exposure: the impact of the individual alpha frequency. International Journal of Radiation Biology, 2022, 98 (5), pp.986-995. ⟨10.1080/09553002.2021.2009146⟩. ⟨hal-03620966⟩