The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Endocrine Connections Année : 2020

The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF

(1, 2) , (3, 4) , (5, 6, 7, 8) , (9, 10) , (10) , (2, 9) , (2) , (10, 2)
1
2
3
4
5
6
7
8
9
10

Résumé

The negative impact of endocrine-disrupting pesticides on human fertility is now a key issue in reproductive health. There are much fewer literature data about the impact of pesticide exposure on women than on men and very few studies of women participating in an in vitro fertilization (IVF) programme. In the present review, we found that (1) various pesticides with an endocrine-disrupting action are associated with poor oocyte maturation and competency, embryonic defects and poor IVF outcomes, and (2) some pesticide compounds are linked to specific causes of female infertility, such as premature ovarian insufficiency, polycystic ovarian syndrome, and endometriosis. IVF participants living in agricultural regions should be informed about the fertility decline, low ongoing pregnancy rates, and elevated risk of miscarriage associated with exposure to high doses of pesticides.

Dates et versions

hal-03545113 , version 1 (27-01-2022)

Identifiants

Citer

Rosalie Cabry, Philippe Merviel, Aicha Madkour, Elodie Lefranc, Florence Scheffler, et al.. The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF. Endocrine Connections, 2020, 9 (6), pp.R134-R142. ⟨10.1530/EC-20-0135⟩. ⟨hal-03545113⟩
22 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook Twitter LinkedIn More