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From global proteome profiling to single targeted molecules of follicular fluid and oocyte: contribution to embryo development and IVF outcome

Abstract : The development of in vitro fertilization (IVF) techniques for infertility management has led to the investigation of the proteome of follicular fluid and oocyte. In addition, different markers contributing to oocyte maturation and embryo development potential have been reported in the literature. Different techniques were utilized to analyze whole proteome or single protein markers in follicular fluid and oocytes, particularly in animal models. Data from several studies have generated large amounts of information, however, an ideal profile to predict the best oocytes and embryos suitable for implantation are still to be uncovered. The identification of such profiles and markers from follicular fluid, oocytes and endometrium should help scientists and clinicians develop better strategies to improving clinical outcome of IVF cycles.
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https://hal-u-picardie.archives-ouvertes.fr/hal-03548064
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Soumis le : samedi 29 janvier 2022 - 14:23:24
Dernière modification le : jeudi 11 août 2022 - 13:14:06

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Moncef Ben Khalifa, Aicha Madkour, Noureddine Louanjli, Nouzha Bouamoud, Brahim Saadani, et al.. From global proteome profiling to single targeted molecules of follicular fluid and oocyte: contribution to embryo development and IVF outcome. Expert Review of Proteomics, Taylor & Francis, 2015, 12 (4), pp.407-423. ⟨10.1586/14789450.2015.1056782⟩. ⟨hal-03548064⟩

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