Complete endoscopic healing is associated with lower disability than partial mucosal healing in Crohn's disease: a prospective multicentric study

Clara Yzet (1, 2) , Franck Brazier (1) , V. Sebbagh (3) , P. Vanelslander (4) , V. Dejour (4) , B. David (5) , E. Nguyen-Khac (1) , M. Diouf (6) , Mathurin Fumery (1, 2)

1 CHU Amiens-Picardie
2 SSPC - Simplification des soins chez les patients complexes - UR UPJV 7518
3 Centre Hospitalier Compiègne-Noyon
4 Polyclinique Saint-Claude
5 TBI - Toulouse Biotechnology Institute
6 UCAD - Université Cheikh Anta Diop de Dakar [Sénégal]

Crohn’s disease (CD) has a significant impact on health status and quality of life, by affecting physical and emotional well-being and by impairment of social and functional abilities. In the era of treat to target concept, endoscopic healing has emerged to be the goal to achieve to prevent intestinal damage and disability. It is not clear what level of endoscopic healing is associated with CD disability. We, therefore, aimed to compare disability associated to complete endoscopic healing or partial endoscopic healing in patients with CD.

Domaines: Sciences du Vivant [q-bio]

Clara Yzet, Franck Brazier, V. Sebbagh, P. Vanelslander, V. Dejour, et al.. Complete endoscopic healing is associated with lower disability than partial mucosal healing in Crohn's disease: a prospective multicentric study. Journal of Crohn's and Colitis, 2021, 15 (1), pp.S248-S249. ⟨10.1093/ecco-jcc/jjab076.302⟩. ⟨hal-03551244⟩