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Short-Term Assessment of Obstructive Sleep Apnea Syndrome Remission Rate after Sleeve Gastrectomy: a Cohort Study

Abstract : BackgroundSevere obesity is associated with a high prevalence of moderate-to-severe obstructive sleep apnea syndrome (OSA). Bariatric surgery has been shown to effectively reduce excess weight and comorbidities.MethodsWe evaluated the remission rate of moderate-to-severe OSA (apnea-hypopnea index (AHI)>= 15) following sleeve gastrectomy. We performed a single-center retrospective chart review of all patients who underwent preoperative polysomnography (PSG) or polygraphy before primary sleeve gastrectomy. Patients with moderate-to-severe OSA treated by continuous positive airway pressure (CPAP) also underwent postoperative PSG. Bivariate analysis was performed to evaluate the criteria associated with remission of moderate-to-severe OSA.ResultsFrom 2013 to 2018, 39 of 162 patients (24.1%) scheduled for sleeve gastrectomy (SG) presented moderate-to-severe OSA requiring CPAP. Postoperative PSG was performed in 36 patients a mean of 9.96.1 months after SG. Mean BMI decreased from 47.4 +/- 8.4 to 36.3 +/- 7.1 kg/m(2) (p<0.001), and all patients reported clinical improvement of OSA symptoms. A remission of moderate-to-severe OSA was observed in 72.2% of patients with a mean decrease of AHI from 45.8 events/h to 11.3 events/h (p<0.001). Postoperative neck circumference was the only factor associated with OSA remission.Conclusion SG is associated with a rapid improvement of moderate-to-severe OSA partially as a result of a reduction of neck circumference. However, the absence of correlation with excess weight loss suggests that other weight-independent factors may also be involved.
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Soumis le : jeudi 3 février 2022 - 16:16:06
Dernière modification le : vendredi 26 août 2022 - 16:14:55




Marine Timmerman, Damien Basille, Aurelie Basille-Fantinato, Mickael E. Baud, Lionel Rebibo, et al.. Short-Term Assessment of Obstructive Sleep Apnea Syndrome Remission Rate after Sleeve Gastrectomy: a Cohort Study. Obesity Surgery, Springer Verlag, 2019, 29 (11), pp.3690-3697. ⟨10.1007/s11695-019-04110-0⟩. ⟨hal-03555478⟩



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