A 4 day-clinical microdialysis monitoring in a patient with traumatic brain injury (tbi) suggests a possible link between brain serotonin and cerebral energy metabolism

B. Renaud; S. Parrot; D. Goncalves; M. Algoud; Marlène Gallet; F. Dailler; L. Denoroy

doi:10.1177/0271678X16639008

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A 4 day-clinical microdialysis monitoring in a patient with traumatic brain injury (tbi) suggests a possible link between brain serotonin and cerebral energy metabolism

B. Renaud ¹ S. Parrot ² D. Goncalves ¹ M. Algoud ¹ Marlène Gallet ² F. Dailler ³ L. Denoroy ²

1 HCL - Hospices Civils de Lyon, Departement de Neurologie

2 CRNL - Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center

3 Intensive Care Unit, Neurological Hospital

Abstract : While the continuous microdialysis monitoring of cerebral biomarkers of energy metabolism is frequently used in neurocritical care, very few data on monoamine neurotransmitters, such as serotonin (5-HT), have been reported using clinical microdialysis. Consequently, taking the opportunity of a feasibility study for a project on TBI, we sought to determine 5-HT levels in the brain microdialysis samples obtained from a TBI patient, concomitantly with biomarkers of energy metabolism.

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B. Renaud, S. Parrot, D. Goncalves, M. Algoud, Marlène Gallet, et al.. A 4 day-clinical microdialysis monitoring in a patient with traumatic brain injury (tbi) suggests a possible link between brain serotonin and cerebral energy metabolism. 27th International Symposium on Cerebral Blood Flow, Metabolism and Function / 12th International Conference on Quantification of Brain Function with PET, Jun 2015, Vancouver, Canada. Journal of Cerebral Blood Flow & Metabolism (Poster Abstracts), 36 (1s), pp.725, 2016, ⟨10.1177/0271678X16639008⟩. ⟨hal-03565048⟩

A 4 day-clinical microdialysis monitoring in a patient with traumatic brain injury (tbi) suggests a possible link between brain serotonin and cerebral energy metabolism

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A 4 day-clinical microdialysis monitoring in a patient with traumatic brain injury (tbi) suggests a possible link between brain serotonin and cerebral energy metabolism

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