Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Intercellular Transmission of Naked Viruses through Extracellular Vesicles: Focus on Polyomaviruses

Abstract : Extracellular vesicles have recently emerged as a novel mode of viral transmission exploited by naked viruses to exit host cells through a nonlytic pathway. Extracellular vesicles can allow multiple viral particles to collectively traffic in and out of cells, thus enhancing the viral fitness and diversifying the transmission routes while evading the immune system. This has been shown for several RNA viruses that belong to the Picornaviridae, Hepeviridae, Reoviridae, and Caliciviridae families; however, recent studies also demonstrated that the BK and JC viruses, two DNA viruses that belong to the Polyomaviridae family, use a similar strategy. In this review, we provide an update on recent advances in understanding the mechanisms used by naked viruses to hijack extracellular vesicles, and we discuss the implications for the biology of polyomaviruses.
Type de document :
Article dans une revue
Liste complète des métadonnées

https://hal-u-picardie.archives-ouvertes.fr/hal-03591566
Contributeur : Louise Dessaivre Connectez-vous pour contacter le contributeur
Soumis le : lundi 28 février 2022 - 16:38:43
Dernière modification le : mardi 22 mars 2022 - 14:36:02

Lien texte intégral

Identifiants

Collections

Citation

Francois Helle, Lynda Handala, Marine Bentz, Gilles Duverlie, Etienne Brochot. Intercellular Transmission of Naked Viruses through Extracellular Vesicles: Focus on Polyomaviruses. VIRUSES-BASEL, 2020, 12 (10), ⟨10.3390/v12101086⟩. ⟨hal-03591566⟩

Partager

Métriques

Consultations de la notice

3