Comparison of Abbott Architect (R), Siemens Immulite (R), and Diasorin Liaison (R) for determination of Epstein-Barr virus serological diagnosis - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Diagnostic Microbiology and Infectious Disease Année : 2018

Comparison of Abbott Architect (R), Siemens Immulite (R), and Diasorin Liaison (R) for determination of Epstein-Barr virus serological diagnosis

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Résumé

This study compared the performance of 3 automated immunoassays, Architect (R) (Abbott), Immulite (R) (Siemens) and Liaison (R) (Diasorin), for Epstein-Barr virus (EBV) serology. Ninety-one serum samples collected in Amiens University Hospital were analyzed for the presence of Viral Capsid Antigen (VCA) IgG and IgM and Epstein Barr Nuclear Antigen (EBNA) IgG. The agreement between the 3 assays was calculated for each marker individually and for determination of the EBV profile, based on interpretation of the combination of these 3 EBV markers. Although similar results were obtained with Architect (R) and Liaison (R), several discordant results were observed with Immulite (R), particularly for EBNA lgG. A large number of EBNA IgG-positive results were observed, which interfered with interpretation of the EBV profile. In contrast, Immulite (R) performed similarly to the 2 other assays for detection of VCA IgM. (C) 2017 Elsevier Inc. All rights reserved.
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Dates et versions

hal-03591575 , version 1 (28-02-2022)

Identifiants

Citer

Catherine Francois, Christine Segard, Maryline Bouvier, Martine Stefanski, Christine Pannier, et al.. Comparison of Abbott Architect (R), Siemens Immulite (R), and Diasorin Liaison (R) for determination of Epstein-Barr virus serological diagnosis. Diagnostic Microbiology and Infectious Disease, 2018, 90 (2), pp.96-101. ⟨10.1016/j.diagmicrobio.2017.10.020⟩. ⟨hal-03591575⟩
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