Bone epithelioid hemangioendotheliom

K. Grondin , S. Salomon , Henri Sevestre (1) , Vincent Goeb (2)

1 LPCM - Laboratoire de Physiologie Cellulaire et Moléculaire - UR UPJV 4667
2 CHU Amiens-Picardie

Introduction. - Epithelioid hemagioendothelioma (HHE) is a rare mesenchymal tumor of vascular origin and epithelial appearance, which develops like angiosarcoma to mimic endothelial cells. According to the literature, its prognosis is variable and remains unpredictable. Case report. - We report a 72-year-old man who presented with an inflammatory pain in the left lower limb. Several osteolytic lesions involving the knee, the upper third of the tibia, the medial malleolus and the left calcaneus were identified. The diagnosis HHE was obtained by histological examination of a bone sample. The patient died after 5 months, despite taxol chemotherapy. Conclusion. - No therapeutic behavior is standardized in this uncommon type of cancer. (C) 2018 Societe Nationale Francaise de Medecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.

Domaines: Sciences du Vivant [q-bio]

K. Grondin, S. Salomon, Henri Sevestre, Vincent Goeb. Bone epithelioid hemangioendotheliom. La Revue de Médecine Interne, 2018, 39 (11), pp.875-878. ⟨10.1016/j.revmed.2018.08.004⟩. ⟨hal-03606084⟩