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Episodic headache with spontaneous hypothermia reveal Shapiro's syndrome variant with effectiveness of clonidine therapy

Abstract : Background Episodic headache with spontaneous hypothermia constitute an uncommon association and is not well recognized in the International Classification of Headache Disorders (ICHD-3). Spontaneous periodic hypothermia, also called Shapiro's syndrome, is a rare disease characterized by hypothermia attacks associated or not with hyperhidrosis without any triggering factor. Case presentation We report a rare case of Shapiro's syndrome variantrevealed by episodes of headache with spontaneous hypothermia witheffectiveness of clonidine therapy in a 76-year-old Parkinson's disease woman. Conclusions In the literature, apart from Shapiro's syndrome, headache withhypothermia seem to occur very rarely. In our case,these symptoms may be considered as a very rare non-motor fluctuation ofParkinson's disease.
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https://hal-u-picardie.archives-ouvertes.fr/hal-03606959
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Soumis le : samedi 12 mars 2022 - 15:16:51
Dernière modification le : dimanche 13 mars 2022 - 03:00:15

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Mickael Aubignat, Melissa Tir, Pierre Krystkowiak, Daniela Andriuta. Episodic headache with spontaneous hypothermia reveal Shapiro's syndrome variant with effectiveness of clonidine therapy. JOURNAL OF HEADACHE AND PAIN, 2021, 22 (1), ⟨10.1186/s10194-021-01245-3⟩. ⟨hal-03606959⟩

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