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Article Dans Une Revue Tetrahedron Année : 2018

Synthesis of phosphorus analogs of TSAO-T

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Résumé

Phosphorus Analogs of TSAO bearing an oxaphospholene ring instead of an oxathiole dioxide ring at C-3' position were prepared. Strategy developed previously on saccharidic moiety was used with introduction of an electron withdrawing alpha group neighboring the phosphorus atom. Biological evaluation on both HIV-1 and HCV showed that these compounds have no activity. (C) 2018 Published by Elsevier Ltd.

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Chimie
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Dates et versions

hal-03613104 , version 1 (18-03-2022)

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Marina Moura, Solen Josse, Denis Postel. Synthesis of phosphorus analogs of TSAO-T. Tetrahedron, 2018, 74 (36), pp.4721-4727. ⟨10.1016/j.tet.2018.07.026⟩. ⟨hal-03613104⟩
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