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Article dans une revue
Solvent- and catalyst-free transamidations of unprotected glycosyl carboxamides
Abstract : The transamidation reactions of unprotected mono- and disaccharidic carboxamides with various primary and secondary arylic, heterocyclic or aliphatic amines are described. This new method is green and atom efficient and gives good to high yields. Notably, the conditions do not require either a solvent or a catalyst and give ammonia as a single by-product. The described coupling reaction is compatible with a variety of functional groups and was used in the synthesis of various glycosidic derivatives and biologically relevant glycolipids. A plausible reaction mechanism involving an intermolecular H-bond activation of the starting carboxamides is proposed.
https://hal-u-picardie.archives-ouvertes.fr/hal-03613738
Contributeur : Louise Dessaivre Connectez-vous pour contacter le contributeur
Soumis le : vendredi 18 mars 2022 - 16:48:22
Dernière modification le : samedi 19 mars 2022 - 03:39:50
Contributeur : Louise Dessaivre Connectez-vous pour contacter le contributeur
Soumis le : vendredi 18 mars 2022 - 16:48:22
Dernière modification le : samedi 19 mars 2022 - 03:39:50