Quantification of Head Tremors in Medical Conditions: A Comparison of Analyses Using a 2D Video Camera and a 3D Wireless Inertial Motion Unit

David Amarantini (1) , Isabelle Rieu (2) , Giovanni Castelnovo (3) , Frederique Fluchere (4) , Chloe Laurencin (5, 6, 7, 8) , Bertrand Degos (9, 10) , Aurelia Poujois (11) , Alexandre Kreisler (12) , Sophie Sangla (13) , Melissa Tir (14) , Isabelle Benatru (15) , Genevieve Blanchet-Fourcade (16) , Dominique Guehl (17) , Dominique Gayraud (18) , Laurent Tatu (19) , Christine Tranchant (20, 21, 22) , Franck Durif (2) , Marion Simonetta-Moreau (23)

1 ToNIC - Toulouse Neuro Imaging Center
2 IP - Institut Pascal
3 CHU Nîmes - Centre Hospitalier Universitaire de Nîmes
4 TIMONE - Hôpital de la Timone [CHU - APHM]
5 CRNL - Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center
6 UCBL - Université Claude Bernard Lyon 1
7 Hôpital neurologique et neurochirurgical Pierre Wertheimer [CHU - HCL]
8 HCL - Hospices Civils de Lyon
9 Hôpital Avicenne [AP-HP]
10 CIRB - Centre interdisciplinaire de recherche en biologie
11 Hôpital Rothschild [AP-HP]
12 Département de Pharmacologie
13 Service de Neurologie [CHU Pitié-Salpêtrière]
14 LNFP - Laboratoire de Neurosciences Fonctionnelles et Pathologies - UR UPJV 4559
15 CIC - Poitiers
16 Centre Hospitalier de Narbonne
17 CHU Bordeaux [Bordeaux]
18 Service de neurologie
19 NEURO - Laboratoire de Neurosciences Intégratives et Cliniques - UFC (UR 481)
20 IGBMC - Institut de Génétique et de Biologie Moléculaire et Cellulaire
21 CHU Strasbourg
22 FMTS - Fédération de Médecine Translationnelle de Strasbourg
23 Service de neurologie

This study compares two methods to quantify the amplitude and frequency of head movements in patients with head tremor: one based on video-based motion analysis, and the other using a miniature wireless inertial magnetic motion unit (IMMU). Concomitant with the clinical assessment of head tremor severity, head linear displacements in the frontal plane and head angular displacements in three dimensions were obtained simultaneously in forty-nine patients using one video camera and an IMMU in three experimental conditions while sitting (at rest, counting backward, and with arms extended). Head tremor amplitude was quantified along/around each axis, and head tremor frequency was analyzed in the frequency and time-frequency domains. Correlation analysis investigated the association between the clinical severity of head tremor and head linear and angular displacements. Our results showed better sensitivity of the IMMU compared to a 2D video camera to detect changes of tremor amplitude according to examination conditions, and better agreement with clinical measures. The frequency of head tremor calculated from video data in the frequency domain was higher than that obtained using time-frequency analysis and those calculated from the IMMU data. This study provides strong experimental evidence in favor of using an IMMU to quantify the amplitude and time-frequency oscillatory features of head tremor, especially in medical conditions.

Domaines: Sciences du Vivant [q-bio]

David Amarantini, Isabelle Rieu, Giovanni Castelnovo, Frederique Fluchere, Chloe Laurencin, et al.. Quantification of Head Tremors in Medical Conditions: A Comparison of Analyses Using a 2D Video Camera and a 3D Wireless Inertial Motion Unit. Sensors, 2022, 22 (6), ⟨10.3390/s22062385⟩. ⟨hal-03634261⟩