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Phantom Study of an In-House Amplitude-Gating Respiratory Method with Silicon Photomultiplier Technology Positron Emission Tomography/Computed Tomography.

Abstract : PURPOSE: The objective of this phantom study was to determine whether breathing-synchronized, silicon photomultiplier (SiPM)-based PET/CT has a suitable acquisition time for routine clinical use. METHODS: Acquisitions were performed in list mode on a 4-ring SiPM-based PET/CT system. The experimental setup consisted of an external respiratory tracking device placed on a commercial dynamic thorax phantom containing a sphere filled with [F-18]-fluorodeoxyglucose. Three-dimensional sinusoidal motion was imposed on the sphere. Data were processed using frequency binning and amplitude binning (the "DMI" and "OFFLINE" methods, respectively). PET sinograms were reconstructed with a Bayesian penalized likelihood algorithm. RESULTS: Respiratory gating from a 150-sec acquisition was successful. The DMI and OFFLINE methods gave similar activity profiles but both were slightly shifted in space; the latter profile was closest to the reference acquisition. CONCLUSION: With SiPM PET/CT systems, the amplitude-based processing of breathing-synchronized data is likely to be feasible in routine clinical practice.
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https://hal-u-picardie.archives-ouvertes.fr/hal-03692953
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Soumis le : vendredi 10 juin 2022 - 10:32:30
Dernière modification le : mardi 14 juin 2022 - 09:32:00

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Pascal Bailly, Roger Bouzerar, Romain Galan, Marc-Etienne Meyer. Phantom Study of an In-House Amplitude-Gating Respiratory Method with Silicon Photomultiplier Technology Positron Emission Tomography/Computed Tomography.. Computer Methods and Programs in Biomedicine, 2022, 221, pp.106907. ⟨10.1016/j.cmpb.2022.106907⟩. ⟨hal-03692953⟩

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