Vitamin D and Cardiovascular Calcification in Chronic Kidney Disease

L. Hénaut (1) , Aurélien Mary (1) , Saïd Kamel (1) , Z.A. Massy (2, 3)

1 MP3CV - Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517
2 CESP - Centre de recherche en épidémiologie et santé des populations
3 Hôpital Ambroise Paré [AP-HP]

Cardiovascular calcification is a common problem among chronic kidney disease (CKD) patients. Altered vitamin D status (another key feature of CKD) has a major impact on mineral and bone disorders, including cardiovascular calcifi- cation. Preclinical and clinical studies have shown that both abnormally low and abnormally high vitamin D levels have local and systemic effects on cardiovascular calcification in CKD patients. This complex situation has major repercussions on the choice and monitoring of the dose of vitamin D prescribed to prevent and/or treat cardiovascular calcification in CKD. \textcopyright Springer International Publishing Switzerland 2016.

Domaines: Sciences du Vivant [q-bio]; Médecine humaine et pathologie

L. Hénaut, Aurélien Mary, Saïd Kamel, Z.A. Massy. Vitamin D and Cardiovascular Calcification in Chronic Kidney Disease. Vitamin D in Chronic Kidney Disease, Springer International Publishing, pp.361--377, 2016, 978-3-319-32507-1 978-3-319-32505-7. ⟨10.1007/978-3-319-32507-1_21⟩. ⟨hal-03702497⟩