Vitamin D and Cardiovascular Calcification in Chronic Kidney Disease

Abstract : Cardiovascular calcification is a common problem among chronic kidney disease (CKD) patients. Altered vitamin D status (another key feature of CKD) has a major impact on mineral and bone disorders, including cardiovascular calcifi- cation. Preclinical and clinical studies have shown that both abnormally low and abnormally high vitamin D levels have local and systemic effects on cardiovascular calcification in CKD patients. This complex situation has major repercussions on the choice and monitoring of the dose of vitamin D prescribed to prevent and/or treat cardiovascular calcification in CKD. \textcopyright Springer International Publishing Switzerland 2016.