Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

Mahadeo Sukhai , Swayam Prabha , Rose Hurren , Angela Rutledge , Anna Lee , Shrivani Sriskanthadevan , Hong Sun (1) , Xiaoming Wang (2) , Marko Skrtic , Ayesh Seneviratne , Maria Cusimano , Bozhena Jhas , Marcela Gronda , Neil Maclean , Eunice Cho , Paul Spagnuolo , Sumaiya Sharmeen , Marinella Gebbia (3, 4, 5) , Malene Urbanus , Kolja Eppert , Dilan Dissanayake , Alexia Jonet , Alexandra Dassonville-Klimpt (6) , Xiaoming Li , Alessandro Datti , Pamela Ohashi , Jeff Wrana , Ian Rogers , Pascal Sonnet (7) , William Ellis , Seth Corey , Connie Eaves , Mark Minden , Jean C.Y. Wang , John Dick , Corey Nislow , Guri Giaever , Aaron Schimmer

1 Princess Margaret Hospital
2 CSIRO Climate Adaptation Flagship and CSIRO Ecosystem Sciences
3 Dana-Farber Cancer Institute [Boston]
4 University of Toronto
5 MSH - Mount Sinai Hospital [Toronto, Canada]
6 LG - Laboratoire des Glucides
7 AGIR - Agents infectieux, résistance et chimiothérapie - UR UPJV 4294

Domaines: Sciences du Vivant [q-bio]

Mahadeo Sukhai, Swayam Prabha, Rose Hurren, Angela Rutledge, Anna Lee, et al.. Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. Journal of Clinical Investigation, 2013, 123 (1), pp.315-328. ⟨10.1172/JCI64180⟩. ⟨hal-03708611⟩