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Antioxidant Properties of Phenolic Compounds from Baccharis articulata and B. usterii

Abstract : As a continuation of our research on the Baccharis genus, the evaluation of the antioxidant effect by TRAP and TBARS assays of three isolated compounds from n-butanol fractions of B. articulata and B. usterii is reported. The structures of these compounds were established as 4- O-β-D-glucopyranosyl-3,5-dimethoxybenzyl-methanol (1), 5- O-[ E]-dicaffeoylquinic acid (2), and 7-hydroxy-5,4′-dimethoxyflavone (3). In the TRAP assay it was possible to observe an antioxidant effect of both n-butanol fractions at 1.25 μg/mL. Among the isolated compounds, compound 2 displayed a remarkable contribution to the total antioxidant capacity of the n-butanol fraction of B. usterii. Moreover, the n-butanol fractions of both species, compounds 1 and 2 at 40.0 μg/mL were efficient in protection of lipid peroxidation in the TBARS experiment. They are promising lead compounds for use in medicinal chemistry studies.
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https://hal-u-picardie.archives-ouvertes.fr/hal-03708782
Contributeur : Pascal Sonnet Connectez-vous pour contacter le contributeur
Soumis le : mercredi 29 juin 2022 - 14:27:01
Dernière modification le : vendredi 5 août 2022 - 11:25:52

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Simone Quintana de Oliveira, Virgínia Demarchi Kappel, Viviane Silva Pires, Claiton Leoneti Lencina, Pascal Sonnet, et al.. Antioxidant Properties of Phenolic Compounds from Baccharis articulata and B. usterii. Natural Product Communications , SAGE Publications, 2014, 9 (7), pp.1934578X1400900. ⟨10.1177/1934578X1400900714⟩. ⟨hal-03708782⟩

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