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Article Dans Une Revue Natural Product Communications Année : 2014

Antioxidant Properties of Phenolic Compounds from Baccharis articulata and B. usterii

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Simone Quintana de Oliveira
  • Fonction : Auteur
Virgínia Demarchi Kappel
  • Fonction : Auteur
Viviane Silva Pires
  • Fonction : Auteur
  • PersonId : 1146071
  • IdRef : 111269121
Claiton Leoneti Lencina
  • Fonction : Auteur
José Cláudio F. Moreira
  • Fonction : Auteur
Grace Gosmann
  • Fonction : Auteur

Résumé

As a continuation of our research on the Baccharis genus, the evaluation of the antioxidant effect by TRAP and TBARS assays of three isolated compounds from n-butanol fractions of B. articulata and B. usterii is reported. The structures of these compounds were established as 4- O-β-D-glucopyranosyl-3,5-dimethoxybenzyl-methanol (1), 5- O-[ E]-dicaffeoylquinic acid (2), and 7-hydroxy-5,4′-dimethoxyflavone (3). In the TRAP assay it was possible to observe an antioxidant effect of both n-butanol fractions at 1.25 μg/mL. Among the isolated compounds, compound 2 displayed a remarkable contribution to the total antioxidant capacity of the n-butanol fraction of B. usterii. Moreover, the n-butanol fractions of both species, compounds 1 and 2 at 40.0 μg/mL were efficient in protection of lipid peroxidation in the TBARS experiment. They are promising lead compounds for use in medicinal chemistry studies.

Dates et versions

hal-03708782 , version 1 (29-06-2022)

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Citer

Simone Quintana de Oliveira, Virgínia Demarchi Kappel, Viviane Silva Pires, Claiton Leoneti Lencina, Pascal Sonnet, et al.. Antioxidant Properties of Phenolic Compounds from Baccharis articulata and B. usterii. Natural Product Communications , 2014, 9 (7), pp.1934578X1400900. ⟨10.1177/1934578X1400900714⟩. ⟨hal-03708782⟩
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