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[Current status of persistent chronic hyperkalaemia in France: An expert consensus based on a Delphi approach].

Résumé : INTRODUCTION: In France, no consensus document on the management of persistent hyperkalaemia is currently available. Variability in clinical practices has been observed. METHODS: A consensus statement on the definition and the management of persistent hyperkalaemia was developed by a Delphi panel of French nephrologists between December 2019 (26~voting participants among 40~invited panellists in first round) and june 2020 (20~voting participants among 26 panellists in second round). RESULTS: Persisting hyperkalaemia not controlled with current treatment strategies may be defined as the occurrence of two or more hyperkalaemia episodes within a year despite the administration of cation-exchange resins or loop diuretics during the same year. Some patient characteristics (diabetes, chronic kidney disease from stage~3B to stage~5 without dialysis, chronic heart failure) are associated with an increased risk of developing persistent hyperkalaemia. There is a medical need for the management of persistent hyperkalaemia in patients treated with renin-angiotensin-aldosterone system inhibitors that is not met by current treatment strategies (including available cation-exchange resins). CONCLUSIONS: The panel expressed a need for new treatment strategies validated by clinical trials.
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https://hal-u-picardie.archives-ouvertes.fr/hal-03716517
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Soumis le : jeudi 7 juillet 2022 - 15:08:40
Dernière modification le : vendredi 5 août 2022 - 11:25:27

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Patrick Rossignol, Bruno Moulin, Jean-Michel Halimi, Pierre Bataille, Laurent Juillard, et al.. [Current status of persistent chronic hyperkalaemia in France: An expert consensus based on a Delphi approach].. NEPHROLOGIE & THERAPEUTIQUE, 2022, pp.S1769-7255(21)00568-X. ⟨10.1016/j.nephro.2021.10.008⟩. ⟨hal-03716517⟩

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