Cutaneous involvement in relapsed multiple myeloma

Valéry Salle (1, 2) , Christophe Attencourt (3) , Marion Chevalier (4) , Lucile Séméria (5) , Xavier Boulu (5) , Jean-Denis Karam (5) , Amar Smail (6) , Jean Schmidt (6, 7) , Pierre Duhaut (1, 2) , Amandine Dernoncourt (1)

1 CHU Amiens-Picardie
2 MP3CV - Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517
3 CHIMERE - CHirurgie, IMagerie et REgénération tissulaire de l’extrémité céphalique - Caractérisation morphologique et fonctionnelle - UR UPJV 7516
4 Thalès Optronique
5 UPJV - Université de Picardie Jules Verne
6 Service de Médecine Interne [CHU Amiens-Picardie]
7 RECIF Amiens - Réseau d'Epidémiologie Clinique International Francophone [Amiens]

Cutaneous involvement in multiple myeloma with extramedullary disease is rare. We report the case of a refractory multiple myeloma patient who developed a cutaneous lesion. Histopathology revealed dermal immature plasma cell infiltrate with a lack of CD138 expression. This cutaneous location was associated with an aggressive clinical course and short survival.

Mots clés: cutaneous involvement; extramedullary disease; immature plasma cells; multiple myeloma

Domaines: Médecine humaine et pathologie

Valéry Salle, Christophe Attencourt, Marion Chevalier, Lucile Séméria, Xavier Boulu, et al.. Cutaneous involvement in relapsed multiple myeloma. Clinical Case Reports, 2022, 10 (9), ⟨10.1002/ccr3.6282⟩. ⟨hal-03778922⟩