WNK1 kinase and its partners Akt, SGK1 and NBC-family Na⁺/HCO3^– cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling

Wanyin Chen (1) , Leonel Nguekeu Zebaze , Jihu Dong (1) , Laëtitia Chezeau (1) , Perrine Inquimbert (2) , Sylvain Hugel (2) , Songlin Niu (3) , Frédéric Bihel (1) , Emmanuel Boutant (4) , Eleonore Real (5) , Pascal Villa (6) , Marie-Pierre Junier (7) , Herve Chneiweiss (8, 9) , Marcel Hibert (10) , Jacques Haiech (10) , Marie-Claude Kilhoffer (1) , Maria Zeniou (1)

1 LIT - Laboratoire d'Innovation Thérapeutique
2 INCI - Institut des Neurosciences Cellulaires et Intégratives
3 IS2M - Institut de Science des Matériaux de Mulhouse
4 LBP - Laboratoire de Biophotonique et Pharmacologie - UMR 7213
5 N&eD - Neurobiologie et Développement
6 IGLBIT - Biomolécules et innovation thérapeutique
7 U894 - Centre de Psychiatrie et Neurosciences
8 NPS-04 - Plasticité gliale et neuro-oncologie = Glial Plasticity
9 NPS - Neuroscience Paris Seine
10 Institut Gilbert-Laustriat : Biomolécules, Biotechnologie, Innovation Thérapeutique

Domains: Life Sciences [q-bio]

Wanyin Chen, Leonel Nguekeu Zebaze, Jihu Dong, Laëtitia Chezeau, Perrine Inquimbert, et al.. WNK1 kinase and its partners Akt, SGK1 and NBC-family Na⁺/HCO3^– cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling. Oncotarget, 2018, 9 (43), pp.27197-27219. ⟨10.18632/oncotarget.25509⟩. ⟨hal-02349611⟩