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Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature

Abstract : Objective. To evaluate the IUI success factors relative to controlled ovarian stimulation (COS) and infertility type, this retrospective cohort study included 1251 couples undergoing homologous IUI. Results. We achieved 13% clinical pregnancies and 11% live births. COS and infertility type do not have significant effect on IUI clinical outcomes with unstable intervention of various couples' parameters, including the female age, the IUI attempt rank, and the sperm quality. Conclusion. Further, the COS used seemed a weak predictor for IUI success; therefore, the indications need more discussion, especially in unexplained infertility cases involving various factors. Indeed, the fourth IUI attempt, the female age over 40 years, and the total motile spermcount <5 x 10(6) were critical in decreasing the positive clinical outcomes of IUI. Those parameter cut-offs necessitate a larger analysis to give infertile couples more chances through IUI before carrying out other ART techniques.
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https://hal-u-picardie.archives-ouvertes.fr/hal-03548060
Contributeur : Louise DESSAIVRE Connectez-vous pour contacter le contributeur
Soumis le : samedi 29 janvier 2022 - 14:23:19
Dernière modification le : dimanche 28 août 2022 - 17:58:45

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Rosalie Cabry-Goubet, Florence Scheffler, Naima Belhadri-Mansouri, Stephanie Belloc, Emmanuelle Lourdel, et al.. Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature. BioMed Research International , 2017, 2017, ⟨10.1155/2017/3512784⟩. ⟨hal-03548060⟩

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