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Article dans une revue

Treatment of Bone and Joint Tuberculosis in France: A Multicentre Retrospective Study

Abstract : Background: Nine percent of all cases of tuberculosis are bone and joint tuberculosis (BJTB). BJTB occurs in two main forms: spinal (STB) and extraspinal (ESTB). The aim of this study was to compare STB with ESTB in terms of diagnosis, treatment and outcomes. Methods: We collected demographic, clinical, microbiological, treatment duration and outcome data for patients with BJTB in a retrospective multicentre study over a 17-year period. Results: Of the 116 patients included in the study, 69 (59.5%) had STB and 47 (40.5%) had ESTB. The median age was higher in the ESTB group. There were significantly more foreign-born patients in the STB group. The median time for diagnosis was longer for ESTB (6 months) than STB (4 months) (p= 0.017). Magnetic resonance imaging was highly reliable for the diagnosis. Direct examination and histology allowed the diagnosis to be made in more than 80% of cases. The median treatment duration of 12 months, regardless of the type of BJTB, was longer than recommended. A favourable outcome was achieved in 91.9% of cases. Conclusion: The management of BJTB remains challenging. An earlier diagnosis should be more effective, reducing the total duration of treatment and leading to better tolerance.
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Soumis le : lundi 28 février 2022 - 15:23:49
Dernière modification le : vendredi 5 août 2022 - 11:25:52


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Aurelie Guillouzouic, Claire Andrejak, Olivia Peuchant, Genevieve Hery-Arnaud, Farida Hamdad, et al.. Treatment of Bone and Joint Tuberculosis in France: A Multicentre Retrospective Study. Journal of Clinical Medicine, MDPI, 2020, 9 (8), 12 p. ⟨10.3390/jcm9082529⟩. ⟨hal-03591322⟩



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