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Article dans une revue

SARS-COV-2 Infection in Children and Red Blood Cell Distribution Width

Abstract : SARS-COV-2 infection due to Coronavirus is highly contagious and causes varying degrees of illness throughout the world. Recent literature has shown an association between red blood cell distribution width (RDW) and adverse outcomes among adult patients with COVID-19. Multiple hypotheses can explain the potential prognostic role of RDW in COVID-19 infection. The aim of this study is to describe RDW values in SARS-COV-2 infected children admitted to the Pediatric Emergency Department to shed light on the potential role of RDW as a prognostic factor in this specific group. Of 1086 tested children observed from March 2020 to April 2021, 36 positive SARS-COV-2 children (0-16 years) did not show clinically significant differences in RDW values according to illness categories, days of hospitalization, presence of multisystem inflammatory syndrome in children (MIS-C), or viral load (cycle threshold (CT) values). This study is the first to investigate this issue in a SARS-COV-2 infected pediatric population. Despite our negative results, given the high incidence of Delta variant in children, the low cost of the examination, its prognostic role described in adults, and its association to other pediatric illnesses, we believe that the role of RDW in SARS-COV-2 infected children should be deeper assessed and that larger collaborative studies on this issue are required.
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https://hal-u-picardie.archives-ouvertes.fr/hal-03592186
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Soumis le : mardi 1 mars 2022 - 10:09:27
Dernière modification le : vendredi 12 août 2022 - 03:41:56

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Hyppolite Tchidjou Kuekou, Lucia Palandri, Suzanne Pouplin, Valerie Lithiao Te, Elena Righi, et al.. SARS-COV-2 Infection in Children and Red Blood Cell Distribution Width. Cureus Journal of Medical Science, Cureus, Inc., 2021, 13 (9), ⟨10.7759/cureus.17837⟩. ⟨hal-03592186⟩

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