Coronavirus-induced autoimmunity

Valery Salle (1, 2)

1 CHU Amiens-Picardie
2 MP3CV - Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517

The pandemic of Coronavirus disease 2019 (COVID-19), caused by a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spotlighted the link between viral infection and autoimmunity. In this review, we focus on coronavirus-induced autoimmunity based on evidence from experimental animal models, SARS-CoV infection with in vitro studies of molecular mimicry and COVID-19 with several clinical reports of autoimmune manifestations of this disease. Further studies will be needed to better characterize the role of SARS-CoV-2 in the development of autoimmunity.

Domaines: Sciences du Vivant [q-bio]

Valery Salle. Coronavirus-induced autoimmunity. Clinical Immunology, 2021, 226, ⟨10.1016/j.clim.2021.108694⟩. ⟨hal-03584599⟩